Clomid / Clomifene Citrate Legal Anti Estrogen Steroids Powder CAS
50-41-9 White powder
|Product name||Clomifene Citrate|
|Other name||serophene; pergotime; clomphid; Clomid|
|CAS register number||50-41-9|
|Appearance||White crystalline powder|
|Package||1kg/aluminium foil bag or as required|
|Usage||can be used as pharmaceutical material|
|Minimum order quantity||10g|
|Shipping||By express courier|
|Shipping leading time||Within 24 hours after receiving the payment|
|Payment options||Western Union, MoneyGram, T/T,Bitcoin|
While it has been claimed that Clomid “stimulates” production of
luteinizing hormone (LH) and therefore of testosterone, in fact
Clomid’s activity is achieved not by stimulation of the
hypothalamus and pituitary, but by blocking their inhibition by
estrogen. Clomid is a mixed estrogen agonist/antagonist
(activator/blocker) which, when bound to the estrogen receptor,
puts it in a somewhat different conformation (shape) than does
estradiol. The estrogen receptor requires binding of an estrogen or
drug at its binding site and also the binding of any of several
cofactors at different sites.
Without the binding of the cofactor, the estrogen receptor is
inactive. Different tissues use different cofactors. Some of these
cofactors are able to bind to the estrogen receptor/Clomid complex,
but others are blocked due to the change in shape. The result is
that in some tissues Clomid acts as an antagonist — the cofactor
used in that tissue cannot bind and so the receptor remains
inactive — and in others Clomid acts as an agonist (activator),
because the cofactors used in that tissue are able to bind.
As for toxicity and side effects, Clomid is considered a very safe
drug. Bodybuilders seldom report any problems, but listed possible
side effects do include hot flashes, nausea, dizziness, headaches
and temporarily blurred vision.
Such side effects usually only appear in females however, as they
feel the effects of estrogen manipulation much more readily than
men. While female athletes can clearly gain some benefit from this
substance, estrogen manipulation is probably not the most
comfortable way to go about cutting up.
Should it still be used for such purposed and side effects do
become pronounced, the drug of course is to be discontinued and (at
least) a break taken from it.
Male users generally find that a daily intake of 50-100 mg (1-2
tablets) over a four to six week period will bring testosterone
production back to an acceptable level. A very common regime of
dosing is; 300 md/day 1, 100 mg/day for days 2-11, and 50 mg/day
for days 12-21. This raise in testosterone should occur slowly but
evenly throughout the period of intake.